Falcon R&D Program
SkylineDx develops diagnostic tests based on gene expression signatures. In our R&D centered partnerships with clinicians and academia, entrepreneurial drive interacts with scientific expertise to tackle unmet needs in personalized healthcare.
In melanoma, this extensive collaboration is named the Falcon R&D Program. As the falcon bird is known as an intelligent creature with unprecedented senses and skills, our R&D program is uniquely equipped to unveil new, detailed insights in the genomic, biologic and clinical nature of melanoma.
Under the wings of the Falcon R&D Program, a series of specific studies and projects is initiated, aimed at developing and introducing an array of diagnostic utilities, to provide physicians with the tools to optimize the clinical pathway of their patients. Not by coincidence, related series of studies are named after birds of prey in the Falcon family.
Peregrine Study Initiative
Advanced stages of research to develop a test that predicts a patient’s prognosis and identifies patients with a high risk for disease relapse who may benefit from early adjuvant therapy.
With the introduction of immunotherapy, the treatment options for metastatic melanoma has changed tremendously. This has led to research interest in many areas of treatment optimization, treatment response, treatment resistance and toxicity management. Early detection and efficacious personalized treatment strategies will impact the overall survival and contribute to the discussion of curing this devastating disease. Biomarkers that drive the tests developed under the Falcon Program are aimed to facilitate these endeavors in early detection and personalized treatment.
CP-GEP Model is the scientific name for Merlin’s underlying algorithm.The CP-GEP model combines the clinicopathologic (CP) variables patient age and tumor thickness with the gene expression (GEP) of 8 genes from the primary tumor to calculate a patient’s risk of nodal metastasis. The genes involved in this model are known to play a role in the development of cancer in general or melanoma specifically.
The Falcon R&D Program aims to build an extensive, global network with research institutes. Not only for research and validation studies within the existing Study Initiatives but as well to broaden the scope of the Falcon Program by starting new Study Initiatives that would entail the whole spectrum of melanoma related clinical utilities. These countries are currently participating.
Falcon’s scientific references
The Falcon R&D Program aims to publish its scientific and clinical research as open access peer reviewed manuscripts, available for every stakeholder in the melanoma field. Click the read more button to find references to scientific abstracts that have been presented at – and published by (international) melanoma related conferences.
Identification of melanoma patients at high risk for disease relapse using a biomarker that includes several variables.
Submitted. To be published soon.